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High frequency of alternative splicing variants of the oncogene in neuroendocrine tumors of the pancreas and breast

Frontiers of Medicine   Pages 907-923 doi: 10.1007/s11684-023-1009-7

Abstract: Box 7-containing FAK variants (FAK<sup>6/7sup>) were observed in 7 (87.56/7sup> was positive in 34 (75.6%) of 45 pancreatic NENs, 19 (47.5>6/7sup> was positive in 14 (93.3%) of 15 BrNECs but 0 in 23 non-NEC breast<sup>6/7sup> in cells.These results suggested that FAK<sup>6/7sup> could be a biomarker of NENs and represent

Keywords： FAK<sup>6/7sup>     SRRM4     neuroendocrine neoplasms     pancreas     breast    

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RNA m<sup>6sup>A modification and its function in diseases

Jiyu Tong, Richard A. Flavell, Hua-Bing Li

Frontiers of Medicine 2018, Volume 12, Issue 4,   Pages 481-489 doi: 10.1007/s11684-018-0654-8

Abstract:

N<sup>6sup>-methyladenosine (m<sup>6sup>A) is the most common post-transcriptional RNAsup>A modification could be installed by m<sup>6sup>A “writers” composed of core catalyticThe function of m<sup>6sup>A is executed by m<sup>6sup>A “readers” that bind to m<sup>6sup>A in different cells under normal or disease conditions.However, the mechanism and the regulatory network of m<sup>6sup>A are still largely unknown.

Keywords： RNA modification     m<sup>6sup>A     immunity     cancer     epigenetics    

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Single and joint effects of HHCB and cadmium on zebrafish (

Lei ZHANG, Jing AN, Qixing ZHOU

Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 3,   Pages 360-372 doi: 10.1007/s11783-011-0353-z

Abstract: Thus, single and joint toxic effects of 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8- hexamethylcyclopenta-gamma

Keywords： 1     3     4     6     7     8-hexahydro-4     6     6     7     8     8-hexamethylcyclopenta-gamma-2-benzopyran (HHCB)     cadmium (Cd)     antioxidant    

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Prevalence of asthma symptoms in Golestan schoolchildren aged 6–7 and 13–14 years in Northeast Iran

Fatemeh Mehravar,Soheil Rafiee,Behnaz Bazrafshan,Mahmoud Khodadost

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 345-350 doi: 10.1007/s11684-016-0462-y

Abstract: This study aimed to examine the prevalence of asthma symptoms in Golestan schoolchildren aged 6–7 and 13–14 years in Northeast Iran.The prevalence rate was compared according to age group (aged 6–7 years vs. aged 13–14 yearsIn this cross-sectional study, 1706 Iranian schoolchildren aged 6–7 and 13–14 years in Golestanndash;7 years) (P <0.05).

Keywords： asthma     asthma symptoms     epidemiology     childhood     chronic disease    

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Therapeutic Characterization of <sup>131sup>I-Labeled Humanized Anti-B7-H3 Antibodies for Radioimmunotherapy Article

Fengqing Fu, Meng Zheng, Shandong Zhao, Yan Wang, Minzhou Huang, Hanqing Chen, Ziyi Huang, Kaijie Zhang, Liyan Miao, Xueguang Zhang

Engineering 2023, Volume 30, Issue 11,   Pages 190-202 doi: 10.1016/j.eng.2023.05.011

Abstract:

B7 homolog 3 (B7-H3) has attracted much attention in glioblastoma (GBM) radioimmunotherapy (RIT) dueIn this study, we report that two specific humanized anti-human B7-H3 antibodies (hu4G4 and hu4H12) derivedfrom mouse anti-human B7-H3 antibodies that were generated by computer-aided design and exclusivelyrecognize membrane expression of B7-H3 by human glioma cells.The biodistribution results of <sup>125sup>I-SPECT imaging were similar to those of <sup>89sup>Zr-PET

Keywords： B7-H3     Radioimmunotherapy     Glioblastoma     Pharmacokinetics     Pharmacodynamics    

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A study on rapid acid chrome black (MB 7) spectrophotometric determination of ClO

Jing DONG, Huilong WANG

Frontiers of Chemical Science and Engineering 2011, Volume 5, Issue 2,   Pages 245-251 doi: 10.1007/s11705-010-1003-x

Abstract: and convenient method for the determination of ClO in water was developed by using acid chrome black 7(MB 7) spectrophotometry in this paper.

Keywords： chlorine dioxide     2     6-dinitro-p-cresol (DNPC)     aluminum oxide     water treatment     MB 7 spectrophotometry    

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Enhancement of open circuit voltage in organic solar cells by doping a fluorescent red dye

Qing LI, Junsheng YU, Yue ZANG, Nana WANG, Yadong JIANG

Frontiers in Energy 2012, Volume 6, Issue 2,   Pages 179-183 doi: 10.1007/s11708-012-0177-y

Abstract: In this paper, 4-(dicyanomethylene)-2-t-butyl-6-(1,1,7,7-tetramethyljulolidyl-9-enyl)-4H-pyran (DCJTB

Keywords： organic solar cells (OSCs)     open circuit voltage     fluorescent dye doping     4-(dicyanomethylene)-2-t-butyl-6-(1     1     7     7-tetramethyljulolidyl-9-enyl)-4H-pyran (DCJTB)    

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Study on Algorithm A<sup>*sup> Based on Dynamic Representation of Binary Tree for Environment and Robotic

Tang Ping,Yang Yimin

Strategic Study of CAE 2002, Volume 4, Issue 9,   Pages 50-53

Abstract: A new algorithm A<sup>*sup> , which plans the path of soccer robots in complicated environments is

Keywords： dynamic binary-tree     algorithm A<sup>*sup>     path planning    

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Clinical significance of CD34<sup>+sup>CD117<sup>dimsup>/CD34<sup>+sup>CD117<sup>brisup> myeloblast-associated

Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 608-620 doi: 10.1007/s11684-021-0836-7

Abstract: t(8;21)(q22;q22) acute myeloid leukemia (AML) is a highly heterogeneous hematological malignancy with a high relapse rate in China. Two leukemic myeloblast populations (CD34 CD117 and CD34 CD117 ) were previously identified in t(8;21) AML, and CD34 CD117 cell proportion was determined as an independent factor for this disease outcome. Here, we examined the impact of CD34 CD117 /CD34 CD117 myeloblast-associated gene expression on t(8;21) AML clinical prognosis. In this study, 85 patients with t(8;21) AML were enrolled. The mRNA expression levels of CD34 CD117 -associated genes ( , , and ) and CD34 CD117 -associated genes ( , , and ) were measured using quantitative reverse transcription PCR. Associations between gene expression and clinical outcomes were determined using Cox regression models. Results showed that patients with high , , or expression had significantly inferior overall survival (OS), whereas those with high or expression showed relatively favorable prognosis. Univariate analysis revealed that CD19, CD34 CD117 proportion, mutation, minimal residual disease (MRD), and expression levels of , , , and were associated with OS. Multivariate analysis indicated that mutation, MRD and and expression levels were independent prognostic variables for OS. Identifying the clinical relevance of CD34 CD117 /CD34 CD117 myeloblast-associated gene expression may provide new clinically prognostic markers for t(8;21) AML.

Keywords： t(8     21)(q22     q22) AML     CD34<sup>+sup>CD117<sup>dimsup>/ CD34<sup>+sup>CD117<sup>brisup> cell population    

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K<sup>+sup> and Na<sup>+sup> fluxes in roots of two Chinese Iris populations

Pinfang LI,Biao ZHANG

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 2,   Pages 144-149 doi: 10.15302/J-FASE-2014016

Abstract: Maintenance of ion homeostasis, particularly the regulation of K and Na uptake, is important for all plants to adapt to salinity. Observations on ionic response to salinity and net fluxes of K , Na in the root exhibited by plants during salt stress have highlighted the need for further investigation. The objectives of this study were to compare salt adaptation of two Chinese Iris ( Pall. var. (Fisch.) Koidz.) populations, and to improve understanding of adaptation to salinity exhibited by plants. Plants used in this study were grown from seeds collected in the Xinjiang Uygur Autonomous Region (Xj) and Beijing Municipality (Bj), China. Hydroponically-grown seedlings of the two populations were supplied with nutrient solutions containing 0.1 (control) and 140 mmol·L NaCl. After 12 days, plants were harvested for determination of relative growth rate and K , Na concentrations. Net fluxes of K , Na from the apex and along the root axis to 10.8 mm were measured using non-invasive micro-test technique. With 140 mmol·L NaCl treatment, shoots for population Xj had larger relative growth rate and higher K concentration than shoots for population Bj. However, the Na concentrations in both shoots and roots were lower for Xj than those for Bj. There was a lower net efflux of K found in population Xj than by Bj in the mature zone (approximately 2.4-10.8 mm from root tip). However, no difference in the efflux of Na between the populations was obtained. Population Xj of continued to grow normally under NaCl stress, and maintained a higher K /Na ratio in the shoots. These traits, which were associated with lower K leakage, help population Xj adapt to saline environments.

Keywords： Koidz     population     K<sup>+sup> and Na<sup>+sup>     ion flux     non-invasive micro-test technique    

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Removal of ammonium and nitrate through Anammox and FeS-driven autotrophic denitrification

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 6, doi: 10.1007/s11783-023-1674-4

Abstract:

● Simultaneous NH4<sup>+sup>/NO3<sup>–sup

Keywords： Anammox     Denitrification     FeS     NH4<sup>+sup>/NO3<sup>−sup>     Sulfammox    

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Resistance of large deformation of the Wushaoling Tunnel F7 soft fault

ZHAO Xufeng, CHEN Haiming, WANG Chunmiao

Frontiers of Structural and Civil Engineering 2007, Volume 1, Issue 1,   Pages 123-127 doi: 10.1007/s11709-007-0013-3

Abstract: In this article, the mechanical characteristics of the squeeze of the F7 fault of the Wushaoling Tunnel

Keywords： F7     deformation     appropriate     construction     mechanical    

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China Engineering Science 2005 Volume 7 Contents

null

Strategic Study of CAE 2005, Volume 7, Issue 12,   Pages 98-102

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Acid Orange 7 degradation using methane as the sole carbon source and electron donor

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 3, doi: 10.1007/s11783-021-1468-5

Abstract:

• AO7 degradation was coupled with anaerobic methane oxidation.

Keywords： Azo dyes     AO7 degradation     Anaerobic methane oxidation     Microbial community     ANME-2d    

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Selective recovery of Cu

Haiping LUO,Bangyu QIN,Guangli LIU,Renduo ZHANG,Yabo TANG,Yanping HOU

Frontiers of Environmental Science & Engineering 2015, Volume 9, Issue 3,   Pages 522-527 doi: 10.1007/s11783-014-0633-5

Abstract: As the bioelectrochemical system, the microbial fuel cell (MFC) and the microbial electrolysis cell (MEC) were developed to selectively recover Cu and Ni ions from wastewater. The wastewater was treated in the cathode chambers of the system, in which Cu and Ni ions were removed by using the MFC and the MEC, respectively. At an initial Cu concentration of 500 mg·L , removal efficiencies of Cu increased from 97.0%±1.8% to 99.0%±0.3% with the initial Ni concentrations from 250 to 1000 mg·L , and maximum power densities increased from 3.1±0.5 to 5.4±0.6 W·m . The Ni removal mass in the MEC increased from 6.8±0.2 to 20.5±1.5 mg with the increase of Ni concentrations. At an initial Ni concentration of 500 mg·L , Cu removal efficiencies decreased from 99.1%±0.3% to 74.2%±3.8% with the initial Cu concentrations from 250 to 1000 mg·L , and maximum power densities increased from 3.0±0.1 to 6.3±1.2 W·m . Subsequently, the Ni removal efficiencies decreased from 96.9%±3.1% to 73.3%±5.4%. The results clearly demonstrated the feasibility of selective recovery of Cu and Ni from the wastewater using the bioelectrochemical system.

Keywords： bioelectrochemical system     Cu<sup>2+sup>     Ni<sup>2+sup>     selective recovery    

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Title Author Date Type Operation

High frequency of alternative splicing variants of the oncogene in neuroendocrine tumors of the pancreas and breast

Journal Article

RNA m<sup>6sup>A modification and its function in diseases

Jiyu Tong, Richard A. Flavell, Hua-Bing Li

Journal Article

Single and joint effects of HHCB and cadmium on zebrafish (

Lei ZHANG, Jing AN, Qixing ZHOU

Journal Article

Prevalence of asthma symptoms in Golestan schoolchildren aged 6–7 and 13–14 years in Northeast Iran

Fatemeh Mehravar,Soheil Rafiee,Behnaz Bazrafshan,Mahmoud Khodadost

Journal Article

Therapeutic Characterization of <sup>131sup>I-Labeled Humanized Anti-B7-H3 Antibodies for Radioimmunotherapy

Fengqing Fu, Meng Zheng, Shandong Zhao, Yan Wang, Minzhou Huang, Hanqing Chen, Ziyi Huang, Kaijie Zhang, Liyan Miao, Xueguang Zhang

Journal Article

A study on rapid acid chrome black (MB 7) spectrophotometric determination of ClO

Jing DONG, Huilong WANG

Journal Article

Enhancement of open circuit voltage in organic solar cells by doping a fluorescent red dye

Qing LI, Junsheng YU, Yue ZANG, Nana WANG, Yadong JIANG

Journal Article

Study on Algorithm A<sup>*sup> Based on Dynamic Representation of Binary Tree for Environment and Robotic

Tang Ping,Yang Yimin

Journal Article

Clinical significance of CD34<sup>+sup>CD117<sup>dimsup>/CD34<sup>+sup>CD117<sup>brisup> myeloblast-associated

Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang

Journal Article

K<sup>+sup> and Na<sup>+sup> fluxes in roots of two Chinese Iris populations

Pinfang LI,Biao ZHANG

Journal Article

Removal of ammonium and nitrate through Anammox and FeS-driven autotrophic denitrification

Journal Article

Resistance of large deformation of the Wushaoling Tunnel F7 soft fault

ZHAO Xufeng, CHEN Haiming, WANG Chunmiao

Journal Article

China Engineering Science 2005 Volume 7 Contents

null

Journal Article

Acid Orange 7 degradation using methane as the sole carbon source and electron donor

Journal Article

Selective recovery of Cu

Haiping LUO,Bangyu QIN,Guangli LIU,Renduo ZHANG,Yabo TANG,Yanping HOU

Journal Article